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Sarah Craus Department of Medicine, Faculty of Medicine and Surgery, University of Malta, Mater Dei Hospital, Msida, Malta
Department of Medicine, Mater Dei Hospital, Msida, Malta

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Mark Gruppetta Department of Medicine, Faculty of Medicine and Surgery, University of Malta, Mater Dei Hospital, Msida, Malta
Department of Medicine, Mater Dei Hospital, Msida, Malta

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inclusion criteria on 30 June 2019 were included, while to estimate incidence rates, patients diagnosed between the beginning of 2008 and the end of 2018 were selected. During this study period, the annual number of inhabitants in the country varied from 413

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0006
Volume/Issue:
Volume 1: Issue 1
Open access
Mark S Stein Knox Private Hospital, Wantirna, Victoria, Australia

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Victor Kalff Molecular Imaging and Therapeutic Nuclear Medicine, Cancer Imaging, Prostate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC), Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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Scott G Williams Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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Declan G Murphy Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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Peter G Colman Department of Diabetes and Endocrinology, The Royal Melbourne Hospital and University of Melbourne Department of Medicine, Parkville, Victoria, Australia

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Michael S Hofman Molecular Imaging and Therapeutic Nuclear Medicine, Cancer Imaging, Prostate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC), Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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. Liraglutide is one such analogue and was found, in a large randomised placebo-controlled trial for type-2 diabetes, to halve prostate cancer incidence, with a hazard ratio of 0.54 (95% confidence limits, 0.38–0.88) ( Marso et al. 2016 , Nauck et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-23-0015
Volume/Issue:
Volume 4: Issue 1
Open access
Edward P Gelmann UArizona Cancer Center, University of Arizona, Tucson, Arizona, USA

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diseases are sure to increase in incidence over the coming decades. Changes in diet, improvements in childhood and adolescent health, decreased incidence of infectious disease, control of HIV, and decreased cardiovascular mortality will all contribute to

Article Type:
Editorial
DOI:
https://doi.org/10.1530/EO-21-0001
Volume/Issue:
Volume 1: Issue 1
Open access
Patrick W Owens Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland

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Terri Patricia McVeigh Cancer Genetics Unit Royal Marsden NHS Foundation Trust, London, England

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Nicola Miller Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland

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Carole Guerin Department of Endocrine Surgery Centre hospitalo-universitaire de La Conception, Assistance Publique Hôpitaux de Marseille, Marseille, France

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Frederic Sebag Department of Endocrine Surgery Centre hospitalo-universitaire de La Conception, Assistance Publique Hôpitaux de Marseille, Marseille, France

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Denis Quill Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland

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Marcia Bell Department of Endocrinology, School of Medicine, National University of Ireland, Galway, Ireland

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Michael J Kerin Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland

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Aoife J Lowery Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, National University of Ireland, Galway, Ireland

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Introduction Thyroid cancer is the most common endocrine malignancy with an increasing incidence recorded over recent decades in Western countries, including Ireland. Genetic factors play a significant role in the determination of thyroid

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0003
Volume/Issue:
Volume 1: Issue 1
Open access
Sara Coelho Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Cláudia Costa Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Ana Paula Santos Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal
Research Center, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Pedro Souteiro Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Joana Oliveira Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Júlio Oliveira Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Isabel Azevedo Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Isabel Torres Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Maria José Bento Department of Epidemiology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal
School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal

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Introduction Incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) has been steadily rising both in the United States and in Europe, with a 6.5-fold increase in incidence observed over the past four decades ( Fraenkel et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-22-0043
Volume/Issue:
Volume 2: Issue 1
Open access
Sandra Pekic School of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center Belgrade, Belgrade, Serbia

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Marko Stojanovic School of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center Belgrade, Belgrade, Serbia

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Vera Popovic School of Medicine, University of Belgrade, Belgrade, Serbia

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pituitary disease had previously undiagnosed pituitary tumors, incidentalomas and clinically relevant pituitary tumors ( Hall et al. 1994 , Burman & Saeger 2006 ). Epidemiological studies show an increased incidence and prevalence of pituitary tumors in

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EO-21-0033
Volume/Issue:
Volume 2: Issue 1
Open access
José V Lima Jr Department of Medicine, Division of Endocrinology and Metabolism, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil
Santa Casa de São Paulo School of Medical Sciences, São Paulo, SP, Brazil
Fleury Group, São Paulo, SP, Brazil

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Nilza M Scalissi Santa Casa de São Paulo School of Medical Sciences, São Paulo, SP, Brazil

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Kelly C de Oliveira Department of Medicine, Division of Endocrinology and Metabolism, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil

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Susan C Lindsey Department of Medicine, Division of Endocrinology and Metabolism, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil

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Caroline Olivati Fleury Group, São Paulo, SP, Brazil

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Elisa Napolitano Ferreira Fleury Group, São Paulo, SP, Brazil

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Claudio E Kater Department of Medicine, Division of Endocrinology and Metabolism, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil

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, 50% had PV in the RET gene, 25% in VHL, and 25% in SDHB genes. For patients in the third decade of life, the incidence of PV was highest for the VHL and SDHB genes (28.6% each), followed by RET , MAX , and NF1 genes (14.2% each). For

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-22-0091
Volume/Issue:
Volume 3: Issue 1
Open access
Sylvia L Asa Department of Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA

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Shereen Ezzat Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

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incidence is about 3.9/100, 000 people ( Tjornstrand et al. 2014 ); one study did a tumor-type analysis of annual incidence that identified 3.5 non-functioning, 1.6 lactotroph, 0.5 somatotroph and 0.2 corticotroph or thyrotroph tumors per 100

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EO-22-0041
Volume/Issue:
Volume 2: Issue 1
Open access
T U Kars Department of Internal Medicine, Necmettin Erbakan University Meram School of Medicine, Konya, Turkey

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M Kulaksızoğlu Division of Endocrinology and Metabolism Disease, Department of Internal Medicine, Necmettin Erbakan University Meram School of Medicine, Meram, Konya, Turkey

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İ Kılınç Department of Biochemistry, Necmettin Erbakan University Meram School of Medicine, Meram, Konya, Turkey

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Introduction Thyroid cancer is the most common cancer of the endocrine system, with a continuously increasing incidence in the last decades ( Pellegriti et al. 2013 ). Papillary thyroid carcinoma is the most prevalent histologic type

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0005
Volume/Issue:
Volume 1: Issue 1
Open access
Poh Shean Wong Endocrine Unit, Medical Department, Hospital Kuala Lumpur, Malaysia

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Subashini Rajoo Endocrine Unit, Medical Department, Hospital Kuala Lumpur, Malaysia

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Hairuddin Achmad Sankala Radiology Department, Hospital Kuala Lumpur, Malaysia

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Mohamed Badrulnizam Long Bidin Endocrine Unit, Medical Department, Hospital Kuala Lumpur, Malaysia

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Background The incidence of lung cancer is increasing worldwide, particularly in developing countries. In the Asia-Pacific region, lung cancer is the most commonly diagnosed cancer among men and the second most common cancer among women after

Article Type:
Case Report
DOI:
https://doi.org/10.1530/EO-22-0064
Volume/Issue:
Volume 2: Issue 1
Open access