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Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan
Department of Pathology, Tohoku University Hospital, Sendai, Japan
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response element (ERE) upstream of the target gene to activate its transcription. IHC, immunohistochemistry; ISH, in situ hybridization; PLA, in situ proximity ligation assay; SWH, southwestern histochemistry; MSI, mass spectrometry imaging
Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan
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Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan
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been reported using PLA. Zieba et al . reported that the binding of estradiol to estrogen receptor (ER)-α can be visualized in breast cancer tissue using in situ PLA. The results revealed that the differences between ERα-positive and ERα
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Department of Pathology, Tohoku University Hospital, Sendai, Japan
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, aromatase negatively regulates intratumoral DHT synthesis in breast cancer tissues. DHT concentrations are higher in ductal carcinoma in situ (DCIS) than in invasive ductal carcinoma tissues, where aromatase expression is higher compared to DCIS tissues
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Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
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Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
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lysosomal and proteosomal degradation of SSTR5 and its downregulation induced by prolonged pasireotide incubation ( Treppiedi et al. 2021 ) ( Fig. 2 ). By in situ proximity ligation assay (PLA), the authors demonstrated a direct binding of FLNA to SSTR
Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center Belgrade, Belgrade, Serbia
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Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center Belgrade, Belgrade, Serbia
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Ivanova S Shorthouse A Shousha S Sinnett D 2011 A rare case of male breast ductal carcinoma in-situ associated with prolactinoma . BMJ Case Reports 2011 bcr0120091421 . ( https://doi.org/10.1136/bcr.01.2009.1421 ) Maruyama S Fujimoto N Yin
