Department of Medicine, Mater Dei Hospital, Msida, Malta
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Department of Medicine, Mater Dei Hospital, Msida, Malta
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this study was to analyse variable factors related to craniopharyngiomas, focusing mainly on epidemiology and tumour characteristics by carrying out a population-based study. Materials and methods Study population and data collection Malta
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Research Center, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal
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School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal
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, Hauso et al . 2008 , Fraenkel et al. 2014 ). According to Surveillance, Epidemiology and End Results database, the current incidence of pancreatic neuroendocrine neoplasms (Pan-NEN) in United States is 0.8/100,000/year ( Dasari et al. 2017
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Background
The 2015 American Thyroid Association (ATA) guidelines added thyroid lobectomy (TL) as the appropriate treatment for low-risk differentiated thyroid cancer (DTC). We aimed to investigate the population-level factors that influence the utilization of TL.
Methods
The Surveillance, Epidemiology and End Results (SEER) database was queried for all DTC patients fitting low-risk criteria as defined by the ATA. Trends in total thyroidectomy (TT) and TL were identified using a Cochrane–Armitage test. Multivariable logistic regression identified patient and socioeconomic characteristics associated with TL, and difference-in-difference analysis was used to control for secular trends over time.
Results
A total of 43,526 patients with low-risk DTC were identified in the SEER database; 39,411 pre-2015 and 4115 post-2015. After 2015, TT continued to outnumber TL (76.2% vs 23.8%), although the rate of TL increased significantly (11.6% to 23.8%, P < 0.001). However, difference-in-difference analysis found that age > 55 (OR 1.11, 95% CI 1.01–1.19, P < 0.001) and rurality (OR 1.16, 95% CI 1.05–1.28, P < 0.001) were independently associated with TT. TL was associated with T1 disease (OR 1.11, 95% CI 1.04–1.19, P = 0.001).
Conclusion
Although the 2015 ATA guideline update led to an increase in TL for low-risk DTC, most patients still underwent TT. Age and neighborhood significantly impact the odds of receiving guideline-appropriate TL for low-risk DTC, especially for T2 disease.
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ME & Friis S 2014 The epidemiology of diabetes and cancer . Current Diabetes Reports 14 535 . ( https://doi.org/10.1007/s11892-014-0535-8 ) Cheng I Caberto CP Lum-Jones A Seifried A Wilkens LR Schumacher FR Monroe KR Lim U
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as primary lesions in the pituitary; only recently has there been a report suggesting the possibility of a true primary pituitary NEC ( Saeger et al. 2021 ). Epidemiology of PitNETs Like other NETs ( Yao et al. 2008 ), PitNETs are now
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-mediated non-alcoholic steatohepatitis (NASH) fibrosis . Biochimica et Biophysica Acta 1862 135 – 144 . ( https://doi.org/10.1016/j.bbadis.2015.10.028 ) Dean DS Gharib H 2008 Epidemiology of thyroid nodules . Best Practice and Research: Clinical
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Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA
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Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA
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Department of Medicine, University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota, USA
Prostate Cancer Foundation, Santa Monica, California, USA
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Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, Minnesota, USA
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, and CYP11α in prostate cancer risk and aggressiveness . Cancer Epidemiology, Biomarkers and Prevention 14 2173 – 2177 . ( https://doi.org/10.1158/1055-9965.EPI-05-0215 ) 10.1158/1055-9965.EPI-05-0215 Dai C Chung YM Kovac E Zhu Z Li J Magi
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Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
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Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
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Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
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lower than PSMA density in mCRPC and that exendin-4 will not be a useful diagnostic imaging tool in patients with mCRPC. Low GLP-1R expression does not discount a potential therapeutic benefit from GLP-1R agonists in prostate cancer. The epidemiology
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(0.20 mg/dL (0.6–1.1)). Renal function was mildly impaired at baseline, as shown by a creatinine level of 1.18 mg/dL (0.5–0.9) and a glomerular filtration rate (estimated by a Chronic Kidney Disease Epidemiology Collaboration method (CDK-EPI)) of 46
Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
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Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
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Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Sydney, New South Wales, Australia
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Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
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Cancer Diagnosis and Pathology Group, Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, Australia
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Department of Endocrinology and metabolism, Royal North Shore Hospital, Sydney, Australia Faculty of Medicine and Health, University of Sydney, Sydney, Australia
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Department of Endocrinology and metabolism, Royal North Shore Hospital, Sydney, Australia Faculty of Medicine and Health, University of Sydney, Sydney, Australia
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Northern Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
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to observations based on the Surveillance Epidemiology and End Results ( Sutton et al. 2022 ) and National Surgery Quality Improvement Program databases ( Ullmann et al. 2019 ). The modest engagement with the ATA recommendations can be partially
