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Laura Gerard Départment d’Oncologie Médicale, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France
European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France

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David Barthelemy CIRCAN (CIRculating CANcer) Platform, Hospices Civils de Lyon, GHS University Hospital, Pierre-Benite, France

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Arnaud Gauthier CIRCAN (CIRculating CANcer) Platform, Hospices Civils de Lyon, GHS University Hospital, Pierre-Benite, France

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Valerie Hervieu European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France
Institut Multi-Site de Pathologie et Biologie Moléculaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France

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Jonathan Lopez European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France
Institut Multi-Site de Pathologie et Biologie Moléculaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France

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Benjamin Gibert INSERM, UMR 1052, Lyon Cancer Research Center, Faculté Laennec, Lyon Cedex 08, France

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Helene Lasolle European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France
Fédération d’Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron Cedex, France

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Laurence Chardon Fédération de Biochimie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron Cedex, France

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Jessica Garcia CIRCAN (CIRculating CANcer) Platform, Hospices Civils de Lyon, GHS University Hospital, Pierre-Benite, France

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Gérald Raverot European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France
INSERM, UMR 1052, Lyon Cancer Research Center, Faculté Laennec, Lyon Cedex 08, France
Fédération d’Endocrinologie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron Cedex, France

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Léa Payen CIRCAN (CIRculating CANcer) Platform, Hospices Civils de Lyon, GHS University Hospital, Pierre-Benite, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France

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Thomas Walter Départment d’Oncologie Médicale, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France
European NeuroEndocrine Tumours Society (ENETS) Lyon Center of Excellence, Lyon, France
Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Cedex, France
INSERM, UMR 1052, Lyon Cancer Research Center, Faculté Laennec, Lyon Cedex 08, France

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Background Neuroendocrine carcinomas (NEC) are associated with paraneoplastic syndrome, such as Cushing’s syndrome, in less than 5% of cases. NEC are usually treated with first-line platinum-etoposide chemotherapy and then with FOLFOX, FOLFIRI

Article Type:
Case Report
DOI:
https://doi.org/10.1530/EO-21-0012
Volume/Issue:
Volume 1: Issue 1
Open access
Stéphanie Larose Division of Endocrinology, Department of Medicine, Centre hospitalier de l’Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada

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Dany Rioux Division of Endocrinology, Department of Medicine, Centre hospitalier universitaire régional, Trois-Rivières, QC, Canada

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Roula Albadine Department of Pathology, Centre hospitalier de l’Université de Montréal, Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada, Montréal, QC, Canada

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André Lacroix Division of Endocrinology, Department of Medicine, Centre hospitalier de l’Université de Montréal (CHUM), Université de Montréal, Montréal, QC, Canada

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Learning points Large-cell neuroendocrine carcinoma (LCNEC) of the lung is a rare cause of ectopic adrenocorticotrophic hormone secretion (EAS) causing paraneoplastic Cushing’s syndrome. Desmopressin, CRH or dexamethasone suppression

Article Type:
Case Report
DOI:
https://doi.org/10.1530/EO-23-0002
Volume/Issue:
Volume 3: Issue 1
Open access
Anna Stroud Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
St Vincent’s Hospital Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia
Garvan Institute of Medical Research, Sydney, Australia

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Pearl Dhaliwal Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
St Vincent’s Hospital Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia
Garvan Institute of Medical Research, Sydney, Australia

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Richard J Harvey Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia

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Raquel Alvarado Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia

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Benjamin P Jonker Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
Faculty of Medicine, Notre Dame University, Sydney, Australia
Institute of Academic Surgery, Royal Prince Alfred Hospital, Sydney, Australia

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Mark J Winder Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
St Vincent’s Hospital Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia
Faculty of Medicine, Notre Dame University, Sydney, Australia

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Jessica W Grayson Rhinology and Skull Base Research Group, St Vincent’s Centre for Applied Medical Research, Sydney, Australia
Department of Otolaryngology Head and Neck Surgery, University of Alabama Birmingham, Birmingham, Alabama, USA

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Ann McCormack St Vincent’s Hospital Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, Australia
Garvan Institute of Medical Research, Sydney, Australia
Department of Endocrinology, St Vincent’s Hospital, Sydney, Australia

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://doi.org/10.1210/jc.2011-2957 ) 10.1210/jc.2011-2957 Invitti C Pecori Giraldi F De Martin M Cavagnini F 1999 Diagnosis and management of Cushing’s syndrome: results of an Italian multicentre study . Journal of Clinical Endocrinology and Metabolism

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0026
Volume/Issue:
Volume 2: Issue 1
Open access
Nadia Gagnon Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Sophie Bernard Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada
Lipids, Nutrition and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Québec, Canada

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Martine Paquette Lipids, Nutrition and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Québec, Canada

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Catherine Alguire Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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André Lacroix Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Pierre-Olivier Hétu Department of Biochemistry, Centre hospitalier de l’Université de Montréal (CHUM), Montreal, Quebec, Canada

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Harold J Olney Department of Medicine, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada

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Isabelle Bourdeau Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Endocrinology 179 G1– G46 . ( https://doi.org/10.1530/EJE-18-0608 ) Greenman Y 2010 Management of dyslipidemia in Cushing’s syndrome . Neuroendocrinology 92 ( Supplement 1 ) 91 – 95 . ( https://doi.org/10.1159/000314294 ) 10.1159/000314294 Hescot S

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0021
Volume/Issue:
Volume 2: Issue 1
Open access
Sara Coelho Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Cláudia Costa Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Ana Paula Santos Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal
Research Center, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Pedro Souteiro Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Joana Oliveira Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Júlio Oliveira Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Isabel Azevedo Department of Medical Oncology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Isabel Torres Department of Endocrinology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal

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Maria José Bento Department of Epidemiology, Portuguese Oncology Institute of Porto, EPE, Porto, Portugal
School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal

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-related Cushing’s syndrome. In our study, we found a higher proportion of arterial hypertension and diabetes mellitus in NET grade 2 and of current or past history of non-neuroendocrine malignancy in NET grade 1. At diagnosis, tumor and hormone secretion

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-22-0043
Volume/Issue:
Volume 2: Issue 1
Open access
Eleanor Fewings Academic Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK

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Serena Khoo Sert Kim Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Alexey Larionov Academic Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK

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Alison Marker Department of Histopathology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Olivier Giger Department of Pathology, University of Cambridge, Cambridge, UK

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Ashley Shaw Department of Radiology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Graeme R Clark Academic Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK

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Vasilis Kosmoliaptsis Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Benjamin G Challis Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Marc Tischkowitz Academic Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK
East Anglian Medical Genetics Service, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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Ruth T Casey Academic Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, UK
Department of Endocrinology, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK

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64 Sex M M F M M M M F F F Presenting feature Incidental Abdominal mass Incidental Incidental Cushing’s syndrome, hypogonadism Hypokalemia and proximal myopathy Incidental Incidental Incidental

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EO-21-0011
Volume/Issue:
Volume 1: Issue 1
Open access