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synchronous PGLs, recommends lifelong surveillance, and is the basis for identifying other at-risk family members. Catecholamine-secreting HNPGLs Catecholamine-secreting HNPGLs are rare with sparse documentation of true incidence rates. This may
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Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
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, paragangliomas (PGL) can occur at various body sites and are traditionally divided into head-and-neck PGL (HNPGL) and PGL located in the thorax, abdomen, or pelvis. The incidence of PPGL is about 0.7 cases per 100,000 persons/year ( Leung et al. 2021 ). The
South Australian Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia
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and Metabolism 104 523 – 538 . ( https://doi.org/10.1210/jc.2018-01071 ) Stiles CE Lloyd G Bhattacharyya S Steeds RP Boomla K Bestwick JP Drake WM 2021 Incidence of cabergoline-associated valvulopathy in primary care patients with prolactinoma using
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Endocrinology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
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prognosis and an incidence between 0.7 and 2 cases per million each year ( Berruti et al. 2021 ). To date, the best curative options are complete tumor resection and treatment with mitotane ( Fassnacht et al. 2018 , Amodru et al. 2020 ). Insulin
Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan
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. Scientific Reports 7 1109. ( https://doi.org/10.1038/s41598-017-01187-4 ) Sung H Ferlay J Siegel RL Laversanne M Soerjomataram I Jemal A Bray F 2021 Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36
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development of Leydig cell stromal tumours, which represent about 1–3% of testicular neoplasms in adults and 3% in children. They have two peaks of incidence: in the third to sixth decade in adults, and in children aged 3–9 years ( Albers et al. 2017
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and Cellular Endocrinology 377 135 – 146 . ( https://doi.org/10.1016/j.mce.2013.07.006 ) Sung H Ferlay J Siegel RL Laversanne M Soerjomataram I Jemal A & Bray F 2021 Global cancer statistics 2020: GLOBOCAN estimates of incidence and