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Christie G Turin Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, University of Colorado, Aurora, Colorado, USA

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Molly M Crenshaw Department of Pediatrics, Combined Pediatrics-Medical Genetics Residency Program, University of Colorado, Aurora, Colorado, USA

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Lauren Fishbein Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, University of Colorado, Aurora, Colorado, USA
Division of Biomedical Informatics and Personalized Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA

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= 26) was 25%, but clearly, the small sample size is a limitation to the study. Another recent retrospective case series that included 91 patients (46 probands) with confirmed SDHC PVs revealed that PCC/PGL incidence in non-probands by age 60 was 6

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Joel George Hampshire Hospitals NHS Trust, Basingstoke, United Kingdom of Great Britain and Northern Ireland

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John Ramage Hampshire Hospitals NHS Trust, Basingstoke, United Kingdom of Great Britain and Northern Ireland

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Benjamin White Hampshire Hospitals NHS Trust, Basingstoke, United Kingdom of Great Britain and Northern Ireland

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Rajaventhan Srirajaskanthan Kings Health Partners NET Centre of Excellence, London, United Kingdom of Great Britain and Northern Ireland

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presence of a clinical syndrome due to excessive hormone secretion, termed carcinoid syndrome (CS), denotes a functional NEN. Carcinoid syndrome The commonest syndrome caused by functional NENs is CS. It has an estimated overall incidence of 1 in

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Nadia Gagnon Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Sophie Bernard Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada
Lipids, Nutrition and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Québec, Canada

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Martine Paquette Lipids, Nutrition and Cardiovascular Prevention Clinic of the Montreal Clinical Research Institute, Montreal, Québec, Canada

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Catherine Alguire Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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André Lacroix Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Pierre-Olivier Hétu Department of Biochemistry, Centre hospitalier de l’Université de Montréal (CHUM), Montreal, Quebec, Canada

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Harold J Olney Department of Medicine, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada

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Isabelle Bourdeau Division of Endocrinology, Department of Medicine, Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montreal, Quebec, Canada

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Introduction Adrenocortical carcinoma (ACC) has an incidence of approximately 1–2 per million population per year ( Bourdeau et al. 2013 ). Staging at presentation remains one of the key prognostic factors with an expected 5-year survival of

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Patricia Gina Lu Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Zhi Ven Fong Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Patrick T Hangge Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Yu-Hui Chang Department of Quantitative Health Sciences, Mayo Clinic in Arizona, Scottsdale, Arizona, USA

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Elisabeth S Lim Department of Quantitative Health Sciences, Mayo Clinic in Arizona, Scottsdale, Arizona, USA

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Nabil Wasif Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Patricia A Cronin Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Chee-Chee Stucky Department of General Surgery, Division of Surgical Oncology and Endocrine Surgery, Mayo Clinic in Arizona, Phoenix, Arizona, USA

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Data source The SEER database comprises cancer incidence data from population-based cancer registries covering approximately 48% of the U.S. population. Unlike other cancer registries, the SEER database is not affiliated with specific hospitals or

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Leo Baxendale-Smith Department of Medical Oncology, Edinburgh Cancer Centre, Western General Hospital, Crewe Road, South, Edinburgh, United Kingdom

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Karim El-Shakankery Department of Medical Oncology, Edinburgh Cancer Centre, Western General Hospital, Crewe Road, South, Edinburgh, United Kingdom

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James Gordon-Smith Department of Interventional Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

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Lucy Wall Department of Medical Oncology, Edinburgh Cancer Centre, Western General Hospital, Crewe Road, South, Edinburgh, United Kingdom

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2022, 12 years after the initial diagnosis and nine years after the diagnosis of metastatic disease. Discussion Adrenocortical carcinoma (ACC) is a rare malignancy with an incidence of one to two cases per million population per year. As such

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Katherine A English OCDEM, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Oxford, UK

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Rajesh V Thakker OCDEM, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Oxford, UK
Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK

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Kate E Lines OCDEM, Radcliffe Department of Medicine, University of Oxford, Churchill Hospital, Oxford, UK
Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK

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Introduction Pancreatic neuroendocrine tumours (PNETs) account for approximately 10% of all pancreatic tumours and occur with an incidence of approximately 1 per 100,000 ( Sonbol et al. 2022 ). The incidence of PNETs is rising, partly due to

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Vineeth Sukrithan Division of Medical Oncology, Department of Internal Medicine, The Ohio State University and Arthur G James Cancer Center, Columbus, Ohio, USA

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Prachi Jain Division of Medical Oncology, Department of Internal Medicine, The Ohio State University and Arthur G James Cancer Center, Columbus, Ohio, USA

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Manisha H Shah Division of Medical Oncology, Department of Internal Medicine, The Ohio State University and Arthur G James Cancer Center, Columbus, Ohio, USA

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Bhavana Konda Division of Medical Oncology, Department of Internal Medicine, The Ohio State University and Arthur G James Cancer Center, Columbus, Ohio, USA

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refractory DTC and MTC have median 10-year survival rates of around 40–42% ( Durante et al. 2006 , Tuttle et al. 2010 , Giunti et al. 2013 ). Poorly DTCs (PDTCs) represent a subset with features that are in between DTC and ATC. The incidence is around

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Lucinda M Gruber Division of Endocrinology, Mayo Clinic, Rochester, Minnesota, USA

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Steven N Hart Department of Computational Pathology and Artificial Intelligence, Mayo Clinic, Rochester, Minnesota, USA

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Louis James Maher III Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA

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& RARECAREnet working group 2020 Incidence and survival of rare cancers in the US and Europe . Cancer Medicine 9 5632 – 5642 . ( https://doi.org/10.1002/cam4.3137 ) Buffet A Burnichon N Favier J & Gimenez-Roqueplo AP 2020 An overview of 20 years of

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Molly Endicott University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Exeter, UK

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Chrissie Thirlwell University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Exeter, UK

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Amy P Webster University of Exeter Medical School, RILD Building, RD&E Hospital Wonford, Exeter, UK

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diabetes generally demonstrate lower prostate-specific antigen levels than individuals without diabetes. This is likely to reduce the detection and diagnosis of prostate cancer, which may also contribute to the reduced incidence of prostate cancer

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Yuko Matsuo Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Kenji Ashida Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Ayako Nagayama Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Kanoko Moritaka Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Mizuki Gobaru Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Junichi Yasuda Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Naoyuki Ogasawara Department of Urology, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Hirofumi Kurose Department of Urology, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Katsuaki Chikui Department of Urology, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Shimpei Iwata Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Yukihiro Inoguchi Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Nao Hasuzawa Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Seiichi Motomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Tsukasa Igawa Department of Urology, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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Masatoshi Nomura Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Asahi-machi, Kurume, Fukuoka, Japan

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.psym.2013.08.008 ) Araki S Kijima T Waseda Y Komai Y Nakanishi Y Uehara S Yasuda Y Yoshida S Yokoyama M Ishioka J , 2019 Incidence and predictive factors of hypoglycemia after pheochromocytoma resection . International Journal of

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